| A. Baseline Resting Pressures (Pves & Pabd) | B. Signal Transmission & Symmetry |
|---|---|
|
• Supine: 5 – 20 cmH2O • Seated: 15 – 40 cmH2O • Standing: 30 – 50 cmH2O • Pdet Baseline (All Positions): -5 to +10 cmH2O |
• Cough Test: Spikes in Pves and Pabd must be equal in amplitude. • Pdet Check: Zero net deflection rules out squeeze and transmission artifacts. |
| Storage Sensations & Normative Volumes | Leak Point Pressures (LPP) & Sphincter Profile |
|---|---|
|
• First Sensation (FS): 100–150 mL (~30-40% MCC) • First Desire (FD): 150–250 mL (~50-60% MCC) • Strong Desire (SD): 250–400 mL (~75-80% MCC) • Max Capacity (MCC): 350–600 mL |
• ALPP > 100 cmH2O: Urethral Hypermobility • ALPP < 60 cmH2O: Intrinsic Sphincter Deficiency (ISD) • DLPP > 40 cmH2O: Upper Tract Risk (High Storage Pdet) • MUCP < 20 cmH2O: Incompetent Urethra (ISD) |
| Male Indices (ICS Abrams-Griffiths) | Female Indices (Solomon-Greenwell) |
|---|---|
|
BOOI (Obstruction Index): PdetQmax - (2 × Qmax) • BOOI > 40 Obstructed • BOOI 20–40 Equivocal • BOOI < 20 Unobstructed BCI (Contractility Index): PdetQmax + (5 × Qmax) • BCI > 150 Strong Contractility • BCI 100–150 Normal Contractility • BCI < 100 Detrusor Underactivity (DU) |
fBOOi (Female BOO Index): PdetQmax - (2.2 × Qmax) • fBOOi > 18 Severe BOO (>90% prob) • fBOOi > 5 Likely BOO (>50% prob) • fBOOi ≤ 5 Unobstructed PIP1 (Provisional Inotropy Index): PdetQmax + Qmax • PIP1 < 30 Weak Contractility • PIP1 30–150 Normal Female Range |
| Condition | Diagnostic Criteria | Clinical Action |
|---|---|---|
| Detrusor Overactivity (DO) | Involuntary Pdet waves during filling | OAB pathway (Antimuscarinics / Beta-3 / Botox) |
| Low Compliance | Compliance < 20 mL/cmH2O | Renal protection, high-pressure lowering therapy |
| Stress Incontinence (SUI) | Involuntary leakage during cough/strain | Evaluate ALPP (< 60 = ISD Risk, > 100 = Hypermobility) |
| MALE PATHWAY (BOOI & BCI) | FEMALE PATHWAY (fBOOi & PIP1) |
|---|---|
|
1. BOOI > 40 & BCI ≥ 100: High probability of surgical success based on EAU criteria (TURP/HoLEP). High recovery chance. 2. BOOI > 40 & BCI < 100: BOO + Detrusor Underactivity. Surgery reduces resistance, but elevated PVR may persist. 3. BOOI < 20 & BCI < 100: Primary Detrusor Underactivity. Surgical outcomes are guarded; focus on CIC or conservative management. |
1. fBOOi > 5: Female Bladder Outlet Obstruction. Investigate anatomical stricture, post-MUS sling over-tensioning, or pelvic floor dysfunction. 2. fBOOi ≤ 5 & PIP1 < 30: Female Detrusor Underactivity. Urethral dilation is not recommended. Focus on conservative emptying strategies (CIC). |
| 1. Symptom Reproduction | 2. Diagnostic Precision | 3. Therapeutic Pathway |
|---|---|---|
| Verify that patient LUTS / incontinence symptoms were accurately reproduced during the test. | Differentiate mechanical outflow resistance from detrusor muscle weakness. | Select appropriate surgical or conservative management based on contractility indices. |